Decreased echinocandin susceptibility in Candida parapsilosis causing candidemia and emergence of a pan-echinocandin resistant case in China

Author:

Ning Yating123,Xiao Meng13,Perlin David S.4,Zhao Yanan4,Lu Minya13ORCID,Li Yi123,Luo Zhengyu123,Dai Rongchen5,Li Shengjie6,Xu Jiajun1,Liu Lingli1,He Hong7,Liu Yun8,Li Fushun9,Guo Yuguang10,Chen Zhongju11,Xu Yingchun13,Sun Tianshu36,Zhang Li13

Affiliation:

1. Department of Laboratory Medicine, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China

2. Graduate School, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China

3. Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases, Beijing, People’s Republic of China

4. Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA

5. School of Public Health, Zhejiang Chinese Medical University, Hangzhou, People’s Republic of China

6. Medical Research Centre, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, People’s Republic of China

7. Department of Clinical Laboratory, the Affiliated Hospital of Qingdao University, Qingdao, People’s Republic of China

8. Department of Laboratory Medicine, Changhai Hospital, Second Military Medical University, Shanghai, People’s Republic of China

9. Department of Laboratory Medicine, The First Hospital of China Medical University, Shenyang, People’s Republic of China

10. Department of Laboratory Medicine, Liaoning Provincial People’s Hospital, Shenyang, People’s Republic of China

11. Department of Laboratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China

Funder

the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences

National High Level Hospital Clinical Research Funding

National Natural Science Foundation of China

National Key R&D Program of China

Beijing Key Clinical Specialty for Laboratory Medicine-Excellent Project

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

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