Transmission experiments support clade-level differences in the transmission and pathogenicity of Cambodian influenza A/H5N1 viruses

Author:

Horwood Paul F.12ORCID,Fabrizio Thomas3ORCID,Horm Srey Viseth1,Metlin Artem1ORCID,Ros Sopheaktra1,Tok Songha1,Jeevan Trushar3,Seiler Patrick3,Y Phalla1,Rith Sareth1,Suttie Annika14,Buchy Philippe15ORCID,Karlsson Erik A.1ORCID,Webby Richard3ORCID,Dussart Philippe1ORCID

Affiliation:

1. Virology Unit, Institut Pasteur du Cambodge, Institut Pasteur International Network, Phnom Penh, Cambodia

2. College of Public Health, Medical and Veterinary Sciences, James Cook University, Townsville, Australia

3. Department of Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, TN, USA

4. School of Applied and Biomedical Sciences, Federation University, Churchill, Australia

5. GlaxoSmithKline Vaccines R&D Intercontinental, Singapore, Singapore

Funder

US Agency for International Development

National Institute of Allergy and Infectious Diseases

National Institutes of Health

Department of Health and Human Services

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

Reference42 articles.

1. Evolution, global spread, and pathogenicity of highly pathogenic avian influenza H5Nx clade 2.3.4.4

2. Emergence of Influenza A(H7N4) Virus, Cambodia

3. World Health Organization. Cumulative number of confirmed human cases of avian influenza A(H5N1) reported to WHO. [cited April 2020]. https://www.who.int/influenza/human_animal_interface/H5N1_cumulative_table_archives/en/

4. Centers for Disease Control and Prevention. Examples of human infections with avian influenza A viruses with possible limited, non-sustained human-to-human transmission. 10 April 2017; [cited April 2020]. Available from https://www.cdc.gov/flu/avianflu/h5n1-human-infections.htm

5. Pathology, Molecular Biology, and Pathogenesis of Avian Influenza A (H5N1) Infection in Humans

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