Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patients

Author:

Andrés Cristina1,Garcia-Cehic Damir23,Gregori Josep34ORCID,Piñana Maria1,Rodriguez-Frias Francisco356,Guerrero-Murillo Mercedes2,Esperalba Juliana1,Rando Ariadna7,Goterris Lidia7ORCID,Codina Maria Gema7ORCID,Quer Susanna2,Martín Maria Carmen1,Campins Magda8ORCID,Ferrer Ricard9ORCID,Almirante Benito10,Esteban Juan Ignacio236,Pumarola Tomás67ORCID,Antón Andrés16ORCID,Quer Josep23ORCID

Affiliation:

1. Respiratory Viruses Unit, Microbiology Department, Vall d’Hebron Institut de Recerca (VHIR), Vall d’Hebron Hospital Universitari, Barcelona, Spain

2. Liver Unit, Liver Diseases - Viral Hepatitis, Vall d’Hebron Institut de Recerca (VHIR), Vall d’Hebron Hospital Universitari, Barcelona, Spain

3. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain

4. Roche Diagnostics SL, Sant Cugat del Valles, Barcelona, Spain

5. Biochemistry and Microbiology Departments, Vall d’Hebron Institut de Recerca (VHIR), Vall d’Hebron Hospital Universitari, Barcelona, Spain

6. Universitat Autònoma de Barcelona, Bellaterra, Spain

7. Microbiology Department, Vall d’Hebron Hospital Universitari, Barcelona, Spain

8. Preventive Medicine, Hospital Vall d’Hebron Hospital Universitari, Barcelona, Spain

9. Intensive Care Department. Shock, Disfunció Orgànica i Ressuscitació (SODIR) Research Group, Vall d’Hebron Institut de Recerca (VHIR), Vall d’Hebron Hospital Universitari, Barcelona, Spain

10. Infectious Diseases Department. Vall d’Hebron Institut de Recerca (VHIR), Vall d’Hebron Hospital Universitari, Barcelona, Spain

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

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