Transmission of fluoroquinolones resistance among multidrug-resistant tuberculosis in Shanghai, China: a retrospective population-based genomic epidemiology study

Author:

Li Minjuan1,Zhang Yangyi234,Wu Zheyuan23,Jiang Yuan23,Sun Ruoyao1,Yang Jinghui5,Li Jing23,Lin Honghua1,Zhang Rui1,Jiang Qi6,Wang Lili23,Wu Xiaocui5,Yu Fangyou5ORCID,Yuan Jianhui7,Yang Chongguang17,Shen Xin23

Affiliation:

1. School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Sun Yat-sen University, Guangdong, People’s Republic of China

2. Division of TB and HIV/AIDS Prevention, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, People’s Republic of China

3. Shanghai Institutes of Preventive Medicine, Shanghai, People’s Republic of China

4. Department of Epidemiology, School of Public Health and Key Laboratory of Public Health Safety, Fudan University, Shanghai, People’s Republic of China

5. Department of Clinical Laboratory, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai, People’s Republic of China

6. Department of Epidemiology and Biostatistics, School of Public Health, Wuhan University, Wuhan, People’s Republic of China

7. Nanshan District Center for Disease Control and Prevention, Shenzhen, People’s Republic of China

Funder

National Key Research

National Natural Science Foundation of China

Science and Technology Innovation Plan of Shanghai Science and Technology Commission

Shanghai Municipal Health Commission

Shenzhen Nanshan district San-Ming project

“Pearl River Talent Plan” Innovation and Entrepreneurship Team Project of Guangdong Province

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

Reference35 articles.

1. World Health Organization. Global tuberculosis report 2022 [Internet]. Geneva: World Health Organization; 2022 [cited 2022 Oct 30]. Available from: https://apps.who.int/iris/handle/10665/363752.

2. The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis

3. WHO consolidated guidelines on drug-resistant tuberculosis treatment [Internet]. Geneva: World Health Organization; 2019 [cited 2022 Jul 25]. Available from: http://www.ncbi.nlm.nih.gov/books/NBK539517/.

4. Resistance to fluoroquinolones and second-line injectable drugs: impact on multidrug-resistant TB outcomes

5. WHO consolidated guidelines on tuberculosis Module 4: treatment – Drug-resistant tuberculosis treatment 2022 update [Internet]. Geneva: World Health Organization; 2022. Available from: https://www.ncbi.nlm.nih.gov/books/NBK588564/.

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