Bispecific Antibodies Provide Broad Neutralization of Emerging Beta-Coronaviruses by Targeting ACE2 and Viral Spikes

Author:

Li Minghui1,Zhao Chaoyue1,Shi Jialu2,Wang Xun1,Liu Yuanchen2,Zhao Xiaoyu1,Cai Guonan1,Chu Hin2,Wang Pengfei1

Affiliation:

1. Shanghai Pudong Hospital, Fudan University Pudong Medical Center, State Key Laboratory of Genetic Engineering, MOE Engineering Research Center of Gene Technology, School of Life Sciences, Shanghai Institute of Infectious Disease and Biosecurity, Fudan University, Shanghai, China

2. State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.

Funder

Program of Science and Technology Cooperation with Hong Kong, Macao and Taiwan

Xiaomi Young Talents Program

National Natural Science Foundation of China Excellent Young Scientists Fund

AI for Science project of Fudan University

National Natural Science Foundation of China

Shanghai Rising-Star Program

Publisher

Informa UK Limited

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