Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro-Reference-Cited by-同舟云学术

Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro

Published:2022-02-10 Issue:1 Volume:11 Page:483-497
ISSN:2222-1751
Container-title:Emerging Microbes & Infections
language:en
Short-container-title:Emerging Microbes & Infections

Author:

Mao Binli¹,Le-Trilling Vu Thuy Khanh²,Wang Kai¹^ORCID,Mennerich Denise²,Hu Jie¹,Zhao Zhenyu¹,Zheng Jiaxin¹,Deng Yingying¹,Katschinski Benjamin²,Xu Shilei³,Zhang Guiji¹,Cai Xuefei¹,Hu Yuan¹^ORCID,Wang Jianwei⁴,Lu Mengji²,Huang Ailong¹,Tang Ni¹,Trilling Mirko²,Lin Yong¹

Affiliation:

1. Key Laboratory of Molecular Biology of Infectious Diseases (Chinese Ministry of Education), Department of Infectious Diseases, The Second Affiliated Hospital, Institute for Viral Hepatitis, Chongqing Medical University, Chongqing, People’s Republic of China

2. Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany

3. Department of General Surgery, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, People’s Republic of China

4. Department of Immunology, College of Basic Medicine, Chongqing Medical University, Chongqing, People’s Republic of China

Funder

National Natural Science Foundation of China

Natural Science Foundation Project of CQ CSTC

Key Scientific and Technological Innovation Project

Chongqing Municipal Education Commission

Venture and Innovation Support Program for Chongqing Overseas Returnees

COVID-19 Emergency Project

Chongqing Medical University

Medical Faculty of the University of Duisburg-Essen