Pharmacological suppression of glycogen synthase kinase-3 reactivates HIV-1 from latency via activating Wnt/β-catenin/TCF1 axis in CD4+ T cells

Author:

Wen Jing12,Li Xin3,Zhao Qing-Xia4,Yang Xiao-Fan5,Wu Meng-Li6,Yan Qihong3,Chang Junbiao6,Wang Haikun1,Jin Xia6,Su Xiao1,Deng Kai5,Chen Ling3,Wang Jian-Hua23

Affiliation:

1. Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, People’s Republic of China

2. University of Chinese Academy of Sciences, Beijing, People’s Republic of China

3. Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, People’s Republic of China

4. Department of Infection, Zhengzhou Sixth People's Hospital, Zhengzhou, People’s Republic of China

5. Institute of Human Virology, Key Laboratory of Tropical Disease Control of Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, People’s Republic of China

6. College of Life Science, Henan Normal University, Xinxiang, People’s Republic of China

Funder

NSFC

Chinese Academy of Sciences

Publisher

Informa UK Limited

Subject

Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology

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