Safety, mucosal and systemic immunopotency of an aerosolized adenovirus-vectored vaccine against SARS-CoV-2 in rhesus macaques
Author:
Affiliation:
1. CanSino Biologics, Tianjin, People’s Republic of China
2. Institute of Biotechnology, Academy of Military Medical Sciences, Beijing, People’s Republic of China
Funder
National Key Research and Development Program of China
Publisher
Informa UK Limited
Subject
Virology,Infectious Diseases,Drug Discovery,General Medicine,Immunology,Microbiology,Parasitology,Epidemiology
Link
https://www.tandfonline.com/doi/pdf/10.1080/22221751.2022.2030199
Reference10 articles.
1. COVID-19 vaccines
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3. SARS ‐CoV‐2 receptor ACE 2 and TMPRSS 2 are primarily expressed in bronchial transient secretory cells
4. Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models
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