1. a Department of Pharmacology National Research , Institute of Chinese Medicine Shih-Pai , Taipei, 11221, Taiwan
2. b Institute of Traditional Medicine National Yang-Ming University Shih-Pai , Taipei, 11221, Taiwan
3. c Department of Biochemistry Kaohsiung , Medical College Kaohsiung , 807, Taiwan
4. d Department of Medical Research , Taichung Veterans General Hospital Taichung , 40705, Taiwan