A specific inhibitor of lactate dehydrogenase overcame the resistance toward gemcitabine in hypoxic mesothelioma cells, and modulated the expression of the human equilibrative transporter-1-Reference-Cited by-同舟云学术

A specific inhibitor of lactate dehydrogenase overcame the resistance toward gemcitabine in hypoxic mesothelioma cells, and modulated the expression of the human equilibrative transporter-1

Published:2016-12-01 Issue:10-12 Volume:35 Page:643-651
ISSN:1525-7770
Container-title:Nucleosides, Nucleotides & Nucleic Acids
language:en
Short-container-title:Nucleosides, Nucleotides & Nucleic Acids

Author:

Giovannetti Elisa¹²,Leon Leticia G.¹²³,Gómez Valentina E.¹,Zucali Paolo A.⁴,Minutolo Filippo⁵,Peters Godefridus J.¹

Affiliation:

1. Department Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands

2. Cancer Pharmacology Lab, AIRC Start-Up Unit, University of Pisa, Pisa, Italy

3. University of La Laguna, La Laguna, Spain

4. Department Oncology, Humanitas Cancer Center, Milano, Italy

5. Department Pharmaceutical Sciences, University of Pisa

Publisher

Informa UK Limited

Subject

Genetics,Molecular Medicine,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/15257770.2016.1149193

Reference27 articles.

1. The European mesothelioma epidemic

2. Phase III Study of Pemetrexed in Combination With Cisplatin Versus Cisplatin Alone in Patients With Malignant Pleural Mesothelioma

3. Phase II Study of Pemetrexed Plus Carboplatin in Malignant Pleural Mesothelioma

4. Second-line treatment for malignant pleural mesothelioma

5. New chemotherapeutics in malignant mesothelioma: effects on cell growth and IL-6 production

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