1. Graduate School of Life Science, Hokkaido University, Sapporo, Japan;
2. Cosmo Bio Co., Ltd, Otaru, Japan;
3. Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Sapporo, Japan;
4. Biotechnology Research Institute for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan