Demethylation of dimethyl phosphonate esters with sodium ethanethiolate: Improved synthesis of 5′-methylene substituted 2′,5′-deoxyribonucleotides-Reference-Cited by-同舟云学术

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Demethylation of dimethyl phosphonate esters with sodium ethanethiolate: Improved synthesis of 5′-methylene substituted 2′,5′-deoxyribonucleotides

Published:2023-01-11 Issue:7 Volume:42 Page:538-546
ISSN:1525-7770
Container-title:Nucleosides, Nucleotides & Nucleic Acids
language:en
Short-container-title:Nucleosides, Nucleotides & Nucleic Acids

Author:

Li Nan-Sheng¹²,Piccirilli Joseph A.²³,Greene Geoffrey L.¹²

Affiliation:

1. Ben May Department for Cancer Research, The University of Chicago, Chicago, Illinois, USA

2. Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, Illinois, USA

3. Department of Chemistry, The University of Chicago, Chicago, Illinois, USA

Funder

Virginia and D. K. Ludwig Fund for Cancer Research

Publisher

Informa UK Limited

Subject

Genetics,Molecular Medicine,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/15257770.2023.2166064

Reference13 articles.

1. Synthesis of Oligoribonucleotides Containing a 2′-Amino-5′-S-phosphorothiolate Linkage

2. The chemical evolution of oligonucleotide therapies of clinical utility

3. The evolution of nucleoside analogue antivirals: A review for chemists and non-chemists. Part 1: Early structural modifications to the nucleoside scaffold

4. Antiviral Nucleoside and Nucleotide Analogs: A Review

5. Synthesis, Properties, and Applications of Oligonucleotides Containing an RNA Dinucleotide Phosphorothiolate Linkage

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