The radiosensitizing effect of fluorocyclopentenyl-cytosine (RX-3117) in ovarian and lung cancer cell lines
Author:
Affiliation:
1. Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands
2. Department of Radio Therapy, VU University Medical Center, Amsterdam, The Netherlands
3. Rexahn Pharmaceuticals, Inc., Rockville, Maryland, USA
Publisher
Informa UK Limited
Subject
Genetics,Molecular Medicine,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/15257770.2016.1216565
Reference28 articles.
1. Concurrent chemotherapy (carboplatin, paclitaxel, etoposide) and involved-field radiotherapy in limited stage small cell lung cancer: a Dutch multicenter phase II study
2. Radiosensitization by Thymidine Phosphorylase Inhibitor in Thymidine Phosphorylase Negative and Overexpressing Bladder Cancer Cell Lines
3. Fluorocyclopentenyl-cytosine with Broad Spectrum and Potent Antitumor Activity
4. Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360)
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1. RX-3117 (Fluorocyclopentenyl-Cytosine)-Mediated Down-Regulation of DNA Methyltransferase 1 Leads to Protein Expression of Tumor-Suppressor Genes and Increased Functionality of the Proton-Coupled Folate Carrier;International Journal of Molecular Sciences;2020-04-14
2. RX-3117 (fluorocyclopentenyl cytosine): a novel specific antimetabolite for selective cancer treatment;Expert Opinion on Investigational Drugs;2019-03-16
3. Synergistic effect and reduced toxicity by intratumoral injection of cytarabine-loaded hyaluronic acid hydrogel conjugates combined with radiotherapy on lung cancer;Investigational New Drugs;2019-02-21
4. Re-emerging Antimetabolites with Novel Mechanism of Action with Respect to Epigenetic Regulation: Basic Aspects;Chemotherapy for Leukemia;2017
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