Process Research on the Preparation of DMT Protected 2′-O-Methoxyethylguanosine for Oligonucleotide Synthesis in Therapeutic Applications
Author:
Affiliation:
1. a Isis Pharmaceuticals, Inc. , Carlsbad , California , USA
2. b Shasun Chemicals and Drugs Ltd. , Chennai , India
Publisher
Informa UK Limited
Subject
Genetics,Molecular Medicine,Biochemistry,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/15257770802271748
Reference26 articles.
1. Crooke , S. T. 1998.Basic principles of antisense therapeutics, inAntisense Therapeutics in Biotechnology & Genetic Engineering Reviews, Vol. 15, 121–157. Hampshire, UK: Intercept Ltd.
2. Antisense therapeutics: from theory to clinical practice
3. KILO-SCALE SYNTHESIS PROCESS FOR 2′-O-(2-METHOXYETHYL)-PYRIMIDINE DERIVATIVES
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1. An Improved Process for the Manufacture of 5′-O-(4,4′-Dimethoxytrityl)-N2-isobutyryl-2′-O-(2-methoxyethyl)guanosine;Organic Process Research & Development;2020-09-23
2. A Status Update of Modified Oligonucleotides for Chemotherapeutics Applications;Current Protocols in Nucleic Acid Chemistry;2011-09
3. Biocatalytic transformation of nucleoside derivatives;Biotechnology Advances;2010-05
4. ChemInform Abstract: Process Research on the Preparation of DMT Protected 2′-O-Methoxyethylguanosine for Oligonucleotide Synthesis in Therapeutic Applications.;ChemInform;2009-01-27
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