An Alternative Advantageous Protocol for Efficient Synthesis of Phosphorothioate Oligonucleotides Utilizing Phenylacetyl Disulfide (PADS)
Author:
Publisher
Informa UK Limited
Subject
Genetics,Molecular Medicine,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1080/15257770601112739
Reference24 articles.
1. Advances in the Synthesis of Oligonucleotides by the Phosphoramidite Approach
2. The Functionalization of Oligonucleotides Via Phosphoramidite Derivatives
3. Antisense Phosphorothioate Oligodeoxyribonucleotide Targeted against ICAM-1: Use of I-Linker to Eliminate 3‘-Terminal Phosphorothioate Monoester Formation
4. Controlled Detritylation of Antisense Oligonucleotides
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1. Crystal structure of a DNA catalyst;Nature;2016-01-06
2. Automated synthesis of phosphorus–sulfur analogs of nucleic acids—25 years on: potential therapeutic agents and proven utility in biotechnology;New Journal of Chemistry;2010
3. A two-step sulfurization for efficient solution-phase synthesis of phosphorothioate oligonucleotides;Tetrahedron Letters;2008-05
4. Model Studies Toward the Synthesis of Thymidine Oligonucleotides with Triazole Internucleosidic LinkagesVia Iterative Cu(I)-Promoted Azide–Alkyne Ligation Chemistry;QSAR & Combinatorial Science;2007-12
5. Nucleotides and nucleic acids; oligo- and polynucleotides;Organophosphorus Chemistry
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