Fibroblast Growth Factor Receptor Inhibitors Reduce Adipogenesis of Orbital Fibroblasts and Enhance Myofibroblastic Differentiation in Graves’ Orbitopathy

Author:

Shih Shyang-Rong123,Liao Shu-Lang45,Shih Chih-Wei6,Wei Yi-Hsuan4,Lu Ting-Xuan7,Chou Chien-Hsiang7,Yen Er-Yen7,Chang Yi-Cheng289,Lin Chia-Chi10,Chi Yu-Chiao111,Yang Wei-Shiung2111213ORCID,Tsai Feng-Chiao27

Affiliation:

1. Department of Internal Medicine, National Taiwan University College of Medicine, Taipei, Taiwan

2. Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

3. Center of Anti-Aging and Health Consultation, National Taiwan University Hospital, Taipei, Taiwan

4. Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan

5. Department of Ophthalmology, National Taiwan University College of Medicine, Taipei, Taiwan

6. Department of Ophthalmology, Zhongxing Branch, Taipei City Hospital, Taipei, Taiwan

7. Department of Pharmacology, National Taiwan University College of Medicine, Taipei, Taiwan

8. Graduate Institute of Medical Genomics and Proteomics, National Taiwan University College of Medicine, Taipei, Taiwan

9. Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan

10. Department of Oncology, National Taiwan University Hospital, Taipei, Taiwan

11. Graduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei, Taiwan

12. Center for Obesity, Lifestyle, and Metabolic Surgery, National Taiwan University Hospital, Taipei, Taiwan

13. Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan

Funder

Ministry of Science and Technology, Taiwan

National Taiwan University Hospital

National Taiwan University

Liver Disease Prevention and Treatment Research Foundation, Taiwan

Wong-Yuan Endocrine Fund in Taiwan

National Health Research Institute,Taiwan

Publisher

Informa UK Limited

Subject

Ophthalmology,Immunology and Allergy

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