The diabetes medication canagliflozin promotes mitochondrial remodelling of adipocyte via the AMPK-Sirt1-Pgc-1α signalling pathway-Reference-Cited by-同舟云学术

The diabetes medication canagliflozin promotes mitochondrial remodelling of adipocyte via the AMPK-Sirt1-Pgc-1α signalling pathway

Published:2020-01-01 Issue:1 Volume:9 Page:484-494
ISSN:2162-3945
Container-title:Adipocyte
language:en
Short-container-title:Adipocyte

Author:

Yang Xuping¹²³,Liu Qinhui³,Li Yanping³,Tang Qin¹³,Wu Tong¹³,Chen Lei¹³,Pu Shiyun¹³,Zhao Yingnan¹³,Zhang Guorong¹³,Huang Cuiyuan¹³,Zhang Jinhang¹³,Zhang Zijing¹³,Huang Ya¹³,Zou Min¹,Shi Xiongjie⁴,Jiang Wei⁵,Wang Rui⁶,He Jinhan¹³

Affiliation:

1. Department of Pharmacy, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University. Chengdu China

2. Department of Pharmacy, The Affiliated Hospital of Southwest Medical University, Luzhou, China

3. Laboratory of Clinical Pharmacy and Adverse Drug Reaction, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu China

4. College of Life Sciences, the Institute for Advanced Studies, Wuhan University, Wuhan, China

5. Molecular Medicine Research Center, West China Hospital of Sichuan University, Chengdu, China

6. Department of Cardiology, Yangpu Hospital, Tongji University, Shanghai, China

Funder

National Natural Science Foundation of China

China Postdoctoral Fellowship

Young Scientist Fellowship of Sichuan University

Postdoctoral Fellowship of Sichuan University

Publisher

Informa UK Limited

Subject

Cell Biology,Histology

Link

https://www.tandfonline.com/doi/pdf/10.1080/21623945.2020.1807850

Reference49 articles.

1. Mitochondrial Dynamics and Metabolic Regulation

2. Regional differences in oxidative capacity of rat white adipose tissue are linked to the mitochondrial content of mature adipocytes

3. Adipocytes as regulators of energy balance and glucose homeostasis

4. The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes

5. Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1

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