An Ethical Argument for Ending Human Trials of Amyloid-Lowering Therapies in Alzheimer’s Disease
Author:
Affiliation:
1. UMR 8011 Sorbonne Université
2. University of Pittsburgh School of Medicine
3. University of Cincinnati
Publisher
Informa UK Limited
Subject
General Neuroscience
Link
https://www.tandfonline.com/doi/pdf/10.1080/21507740.2022.2129858
Reference9 articles.
1. CIOMS (Council for International Organizations of Medical Sciences). 2002. International ethical guidelines for biomedical research involving human subjects. https://cioms.ch/publications/product/international-ethical-guidelines-for-biomedical-research-involving-human-subjects-2/
2. Alzheimer's disease drug development pipeline: 2022
3. The Accelerated Approval of Aducanumab Invites a Rethink of the Current Model of Drug Development for Alzheimer's Disease
4. Acknowledgment of uncertainty: A fundamental means to ensure scientific and ethical validity in clinical research
5. Soluble Amyloid-β Consumption in Alzheimer’s Disease
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1. Ethical Issues Around Treatment-Induced Amyloid-Related Imaging Abnormalities in Alzheimer's Disease;Journal of Radiology Nursing;2024-09
2. Estimated effects of amyloid reduction on cognitive change: A Bayesian update across a range of priors;Alzheimer's & Dementia;2023-10-30
3. Recent Updates on the Development of Therapeutics for the Targeted Treatment of Alzheimer’s Disease;Current Pharmaceutical Design;2023-10
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5. From Association to Intervention: The Alzheimer’s Disease-Associated Processes and Targets (ADAPT) Ontology;Journal of Alzheimer's Disease;2023-07-25
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