Statistical Assessment of QT/QTc Prolongation Based on Maximum of Correlated Normal Random Variables-Reference-Cited by-同舟云学术

Statistical Assessment of QT/QTc Prolongation Based on Maximum of Correlated Normal Random Variables

Published:2008-05-08 Issue:3 Volume:18 Page:494-501
ISSN:1054-3406
Container-title:Journal of Biopharmaceutical Statistics
language:en
Short-container-title:Journal of Biopharmaceutical Statistics

Author:

Cheng Bin¹,Chow Shein-Chung²,Burt David³,Cosmatos Dennis³

Affiliation:

1. a Department of Biostatistics , Columbia University , New York, New York, USA

2. b Department of Biostatistics and Bioinformatics , Duke University School of Medicine , Durham, North Carolina, USA

3. c Biostatistics for Translational Development, Wyeth Research , Collegeville, Pennsylvania, USA

Publisher

Informa UK Limited

Subject

Pharmacology (medical),Pharmacology,Statistics and Probability

Link

https://www.tandfonline.com/doi/pdf/10.1080/10543400802020987

Reference7 articles.

1. A Confidence Interval for the Maximal Mean QT Interval Change Caused by Drug Effect

2. A Simulation Study of Power in Thorough QT/QTc Studies and a Normal Approximation for Planning Purposes

3. ICH ( 2005 ). ICH E14 Guidance on The Clinical Evaluation of QT/QTc Interval Prolongation and Proarrythmic Potential for Non-Antiarrythmic Drugs . Geneva , Switzerland : International Conference on Harmonisation , May 2005 .

4. Evaluation of Drug-Induced QT Interval Prolongation

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