Sample Size Re-Estimation for Adaptive Sequential Design in Clinical Trials
Author:
Affiliation:
1. a Biostatistics , The Medicines Company , Parsippany, New Jersey, USA
2. b Harvard School of Public Health , Boston, Massachusetts, USA
3. c Cytel Corporation , Cambridge, Massachusetts, USA
Publisher
Informa UK Limited
Subject
Pharmacology (medical),Pharmacology,Statistics and Probability
Link
https://www.tandfonline.com/doi/pdf/10.1080/10543400802369053
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1. Increasing the sample size when the unblinded interim result is promising
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