Adaptive Designs for Dose-Finding Studies Based on Sigmoid E max Model
Author:
Affiliation:
1. a Wyeth Research , Collegeville, Pennsylvania, USA
2. b Department of Statistics , Temple University , Philadelphia, Pennsylvania, USA
Publisher
Informa UK Limited
Subject
Pharmacology (medical),Pharmacology,Statistics and Probability
Link
https://www.tandfonline.com/doi/pdf/10.1080/10543400701643954
Reference16 articles.
1. Box , G. E. P. Hunter , W. G. ( 1963 ). Sequential design of experiments for nonlinear models . In: Proceedings of IBM Scientific Computing Symposium (Statistics) . pp. 113 – 137 .
2. Adaptive designs for dose-finding based on efficacy–toxicity response
3. Model-Oriented Design of Experiments
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