Adaptive Designs for Dose-Finding Studies Based on Sigmoid E max Model

Author:

Dragalin Vladimir1,Hsuan Francis2,Padmanabhan S. Krishna12

Affiliation:

1. a Wyeth Research , Collegeville, Pennsylvania, USA

2. b Department of Statistics , Temple University , Philadelphia, Pennsylvania, USA

Publisher

Informa UK Limited

Subject

Pharmacology (medical),Pharmacology,Statistics and Probability

Reference16 articles.

1. Box , G. E. P. Hunter , W. G. ( 1963 ). Sequential design of experiments for nonlinear models . In: Proceedings of IBM Scientific Computing Symposium (Statistics) . pp. 113 – 137 .

2. Adaptive designs for dose-finding based on efficacy–toxicity response

3. Model-Oriented Design of Experiments

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