Estimating human ADME properties, pharmacokinetic parameters and likely clinical dose in drug discovery
Author:
Affiliation:
1. Drug Metabolism and Pharmacokinetics, Evotec, Abingdon, UK
Funder
Evotec
Publisher
Informa UK Limited
Subject
Drug Discovery
Link
https://www.tandfonline.com/doi/pdf/10.1080/17460441.2019.1660642
Reference96 articles.
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4. Prediction of Human Pharmacokinetics From Preclinical Information: Comparative Accuracy of Quantitative Prediction Approaches
5. Selection of the First-Time Dose in Humans: Comparison of Different Approaches Based on Interspecies Scaling of Clearance
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