Radiosensitivity of rhesus nonhuman primates: consideration of sex, supportive care, body weight, and age at time of exposure

Author:

Singh Vijay K.12ORCID,Carpenter Alana D.12ORCID,Janocha Brianna L.12ORCID,Petrus Sarah A.12ORCID,Fatanmi Oluseyi O.12ORCID,Wise Stephen Y.12ORCID,Seed Thomas M.3

Affiliation:

1. Division of Radioprotectants, Department of Pharmacology and Molecular Therapeutics, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, USA

2. Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, MD, USA

3. Tech Micro Services, Bethesda, MD, USA

Funder

National Institute of Allergy and Infectious Diseases

Congressionally Directed Medical Research Programs

Defense Threat Reduction Agency

Uniformed Services University of the Health Sciences/Armed Forces Radiobiology Research Institute

Publisher

Informa UK Limited

Subject

Drug Discovery

Reference42 articles.

1. Total body irradiation models in NHPs – consideration of animal sex and provision of supportive care to advance model development

2. A review of radiation countermeasures focusing on injury-specific medicinals and regulatory approval status: part I. Radiation sub-syndromes, animal models and FDA-approved countermeasures

3. Radiation Accidents and Nuclear Energy: Medical Consequences and Therapy

4. U.S. Food and Drug Administration. Animal Rule information. 2022. Available at: http://www.fda.gov/EmergencyPreparedness/Counterterrorism/MedicalCountermeasures/MCMRegulatoryScience/ucm391604.htm [Last accessed Oct 20, 2022]

5. U.S. Food and Drug Administration. Animal Rule approvals. 2022. Available at: https://www.fda.gov/drugs/nda-and-bla-approvals/animal-rule-approvals [Last accessed December 5, 2022] There is a list of all drugs approved by US FDA following Animal Rule.

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