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Enabling drug discovery and development through single-cell imaging

Published:2018-12-24 Issue:2 Volume:14 Page:115-125
ISSN:1746-0441
Container-title:Expert Opinion on Drug Discovery
language:en
Short-container-title:Expert Opinion on Drug Discovery

Author:

Pomerantz Andrea K.¹,Sari-Sarraf Farid¹,Grove Kerri J.²,Pedro Liliana²,Rudewicz Patrick J.²,Fathman John W.³,Krucker Thomas⁴

Affiliation:

1. Analytical Sciences & Imaging, Novartis Institutes for BioMedical Research Inc., Cambridge, MA, USA

2. Global Discovery Chemistry, Novartis Institutes for BioMedical Research Inc., Emeryville, CA, USA

3. Cancer Therapeutics, Genomics Institute of the Novartis Research Foundation, La Jolla, CA, USA

4. Alliance Management and Partnering, Novartis Institutes for BioMedical Research Inc., Emeryville, CA, USA

Funder

Novartis Institute of Biomedical Research

Publisher

Informa UK Limited

Subject

Drug Discovery

Link

https://www.tandfonline.com/doi/pdf/10.1080/17460441.2019.1559147

Reference95 articles.

1. The market for chimeric antigen receptor T cell therapies

2. A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

3. Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

4. Light-activated cell identification and sorting (LACIS) for selection of edited clones on a nanofluidic device

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1. Embedded Blur-Free Single-Image Acquisition Pipeline for Droplet Microfluidic Imaging Flow Cytometry (IFC);IEEE Access;2024

2. Recent Advances in Mass Spectrometry-Based Spatially Resolved Molecular Imaging of Drug Disposition and Metabolomics;Drug Metabolism and Disposition;2023-06-09

3. Microfluidics-Enabled Isolation and Single-Cell Analysis of Circulating Tumor Cells;Methods in Molecular Biology;2023

4. From imaging a single cell to implementing precision medicine: an exciting new era;Emerging Topics in Life Sciences;2021-12-10

5. The prospects of tumor chemosensitivity testing at the single-cell level;Drug Resistance Updates;2021-01

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