Lost in translation? A critical look at the role that animal models of obsessive compulsive disorder play in current drug discovery strategies
Author:
Affiliation:
1. Centro de Investigación en Reproducción Animal, CINVESTAV-Universidad Autónoma de Tlaxcala, Tlaxcala, México
2. Doctorado en Ciencias Biológicas, Universidad Autónoma de Tlaxcala, Tlaxcala, México
Funder
funded
Publisher
Informa UK Limited
Subject
Drug Discovery
Link
https://www.tandfonline.com/doi/pdf/10.1080/17460441.2018.1417379
Reference97 articles.
1. Reappraisal of spontaneous stereotypy in the deer mouse as an animal model of obsessive-compulsive disorder (OCD): Response to escitalopram treatment and basal serotonin transporter (SERT) density
2. 5-HT2A/C receptors do not mediate the attenuation of compulsive checking by mCPP in the quinpirole sensitization rat model of obsessive–compulsive disorder (OCD)
3. The signal attenuation rat model of obsessive–compulsive disorder: a review
4. Effects of 5-HT uptake inhibitors, agonists and antagonists on the burying of harmless objects by mice; a putative test for anxiolytic agents
5. Animal models of obsessive compulsive disorder: recent findings and future directions
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2. Sex differences in the anticompulsive-like effect of memantine: Involvement of nitric oxide pathway but not AMPA receptors;Behavioural Brain Research;2024-03
3. Artificial intelligence pushes the boundaries of behavioral analysis in drug discovery: a revolution from the deep;Expert Opinion on Drug Discovery;2023-11-10
4. EPD1504: a novel μ-opioid receptor partial agonist attenuates obsessive–compulsive disorder (OCD)-like behaviors;Frontiers in Psychiatry;2023-06-30
5. Sex Differences in the Anticompulsive-Like Effect of Memantine: Involvement of Nitric Oxide Pathway But Not Ampa Receptors;2023
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