How can we improve the design of small molecules to target thioredoxin reductase for treating cancer?-Reference-Cited by-同舟云学术

How can we improve the design of small molecules to target thioredoxin reductase for treating cancer?

Published:2020-12-14 Issue:4 Volume:16 Page:331-333
ISSN:1746-0441
Container-title:Expert Opinion on Drug Discovery
language:en
Short-container-title:Expert Opinion on Drug Discovery

Author:

Xu Jianqiang¹,Fang Jianguo²

Affiliation:

1. School of Life and Pharmaceutical Sciences (LPS) and Panjin Institute of Industrial Technology (PIIT), Dalian University of Technology, Panjin, China

2. State Key Laboratory of Applied Organic Chemistry & College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, China

Funder

National Natural Science Foundation of China

Publisher

Informa UK Limited

Subject

Drug Discovery

Link

https://www.tandfonline.com/doi/pdf/10.1080/17460441.2021.1854220

Reference18 articles.

1. Targeting the Thioredoxin System for Cancer Therapy

2. The A to Z of modulated cell patterning by mammalian thioredoxin reductases

3. Small molecule inhibitors of mammalian thioredoxin reductase

4. Targeting the Selenoprotein Thioredoxin Reductase 1 for Anticancer Therapy

5. Thioredoxin reductase inhibitors: a patent review

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3. Unraveling redox pathways of the disulfide bond in dimethyl disulfide: Ab initio modeling;Journal of Molecular Modeling;2024-05-23

4. Editorial: Small molecule inhibitors targeting mammalian selenoprotein thioredoxin reductases (TXNRDs): Interactions, mechanisms, and applications;Frontiers in Molecular Biosciences;2023-02-02

5. QSAR, molecular docking, and molecular dynamics simulation–based design of novel anti-cancer drugs targeting thioredoxin reductase enzyme;Structural Chemistry;2023-01-20