The roles of human induced pluripotent stem cell-derived cardiomyocytes in drug discovery: managing in vitro safety study expectations
Author:
Affiliation:
1. Department of Integrative Pharmacology (ZR13), AP-9A-LL, AbbVie Inc., North Chicago, IL, USA
2. Novartis Institutes for Biomedical Research, Safety Pharmacology, Basel, Switzerland
Funder
not funded
Publisher
Informa UK Limited
Subject
Drug Discovery
Link
https://www.tandfonline.com/doi/pdf/10.1080/17460441.2020.1736549
Reference84 articles.
1. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2. Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
3. Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?
4. Maturing human pluripotent stem cell-derived cardiomyocytes in human engineered cardiac tissues
5. Current methods for the maturation of induced pluripotent stem cell-derived cardiomyocytes
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