Water-soluble HPMA copolymer—prostaglandin E1conjugates containing a cathepsin K sensitive spacer
Author:
Publisher
Informa UK Limited
Subject
Pharmaceutical Science
Link
http://www.tandfonline.com/doi/pdf/10.1080/10256018808623883
Reference72 articles.
1. Synthesis and pharmacological activity of a novel water-soluble hepatocyte-specific polymeric prodrug of prostaglandin E 1 using lactosylated poly( l -glutamic hydrazide) as a carrier 1 1Abbreviations: PGE1, prostaglandin E1; PLGA-HZ, poly(l-glutamic hydrazide); Lac-NH-PLGA, lactosylated poly(l-glutamic hydrazide); PGE1 conjugate, prostaglandin E1 prodrug using Lac-NH-PLGA as a carrier; DTPA anhydride, diethylenetriamine-N,N,N′,N″,N″-pentaacetic dianhydride; GPT, glutamic pyruvic transaminase; AUC, area under the plasma concentration-time curve; ROS, reactive oxygen species; and EP receptor, receptor for prostaglandins expressed on a plasma membrane.
2. L-trans-Epoxysuccinyl-leucylamido(4-guanidino)butane (E-64) and its analogues as inhibitors of cysteine proteinases including cathepsins B, H and L
3. Cysteine proteases as therapeutic targets
4. Human Cathepsin O2, a Novel Cysteine Protease Highly Expressed in Osteoclastomas and Ovary Molecular Cloning, Sequencing and Tissue Distribution
5. Human Cathepsin O2, a Matrix Protein-degrading Cysteine Protease Expressed in Osteoclasts
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