Synthesis of New Aromatic Pyrrolo[2,1- c] [1,4]benzodiazepines and Pyrrolo[1,2- a] thieno[3,2- e] [1,4]diazepines as Anti-tumoral Agents
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Published:2002-01-01
Issue:6
Volume:17
Page:403-407
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ISSN:1475-6366
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Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
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language:en
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Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
Author:
Lisowski Vincent1, Fabis Frédéric1, Pierré Alain2, Caignard Daniel-Henri2, Renard Pierre2, Rault Sylvain1
Affiliation:
1. Centre d'Etudes et de Recherche sur le Médicament de Normandie-UFR des Sciences Pharmaceutiques 5, rue Vaubénard 14032 Caen cedex, France 2. ADIR, 1 rue Carle Hébert 92415 Courbevoie Cedex, France
Publisher
Informa UK Limited
Subject
Drug Discovery,Pharmacology,General Medicine
Reference10 articles.
1. Lisowski, V., Enguehard, C., Lancelot, J.C., Caignard, D.H., Lambel, S., Leonce, S., Pierre, A., Atassi, G., Renard, P. and Rault, S. (2001) "Design, synthesis and antiproliferative activity of tripentones: a new series of antitubulin agents", Bioorganic and Medicinal Chemistry Letters 11, 2205-2208. 2. Thurstan, D.E. and Bose, D.S. (1994) "Synthesis of DNAInteractive Pyrrolo[2,1-c][1,4]benzodiazepines", Chemical Reviews 94, 433-465. 3. Thurstan, D.E. (1993) "Advances in the study of pyrrolo[2,1c][1,4]benzodiazepines (PBD) antitumour antibiotics", Molecular Aspects of Anticancer Drug-DNA Interactions (The Macmillan Press Ltd., London, U.K.), pp 54-88. 4. Fabis, F., Sopkova-de Oliveira Santos, J., Fouchet-Jolivet, S. and Rault, S. (2001) "An expedient route to aromatic pyrrolo[2,1-c][1,4]benzodiazepines and a study of their reactivity", Tetrahedron Letters 42,5183-5185. 5. Fabis, F., Jolivet-Fouchet, S., Robba, M., Landelle, H. and Rault, S. (1998) "Thiaisatoic anhydrides: efficient synthesis under microwave heating conditions and study of their reactivity", Tetrahedron 54,10789-10800.
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