2070-DTI, A Topoisomerase Inhibitor Produced byStreptomycessp. Strain No. 2070
Author:
Affiliation:
1. Department of Pharmaceutical Microbiology, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, 862-0973, Kumamoto, Japan
Publisher
Informa UK Limited
Subject
Drug Discovery,Pharmacology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/14756360310001613076
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1. Adriamycin-Induced DNA Damage Mediated by Mammalian DNA Topoisomerase II
2. Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.
3. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.
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