In vitro and in vivo trypanocidal activity of the ethyl esters of N-allyl and N-propyl oxamates using different Trypanosoma cruzi strains
Author:
Affiliation:
1. Departamento de Bioquímica y
2. Departamento de Parasitología, Escuela Nacional de Ciencias Biológicas- Instituto Politécnico Nacional, Apartado Postal 4-129, Admon. 4, México City, 06401, México
Publisher
Informa UK Limited
Subject
Drug Discovery,Pharmacology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/14756360601051233
Reference25 articles.
1. Progress towards interruption of transmission of Chagas disease
2. Parasitological cure of Chagas disease: is it possible? Is it relevant?
3. Comparative studies of nifurtimox uptake and metabolism by drug-resistant and susceptible strains of Trypanosoma cruzi
4. Trypanosoma cruzi: inhibition of alpha-hydroxyacid dehydrogenase isozyme II by N-allyl and N-propyl oxamates and their effects on intact epimastigotes
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1. Trypanothione Reductase and Superoxide Dismutase as Current Drug Targets for Trypanosoma cruzi: An Overview of Compounds with Activity against Chagas Disease;Current Medicinal Chemistry;2017-05-31
2. Trypanocidal effect of the benzyl ester of N-propyl oxamate: a bi-potential prodrug for the treatment of experimental Chagas disease;BMC Pharmacology and Toxicology;2015-04-22
3. Inhibition of lactate dehydrogenase activity as an approach to cancer therapy;Future Medicinal Chemistry;2014-03
4. Decreased Intensity of Inflammation in Benznidazole-Treated Mice Inoculated with Trypanosoma cruzi I Stocks from Mexico and Persistence of Circulating Parasites;The American Journal of Tropical Medicine and Hygiene;2012-10-03
5. Trypanosoma cruzi: Desferrioxamine decreases mortality and parasitemia in infected mice through a trypanostatic effect;Experimental Parasitology;2011-08
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