Cytotoxic and Topographical Properties of 6-Arylidene-2-dimethylaminomethylcyclohexanone Hydrochlorides and Related Compounds-Reference-Cited by-同舟云学术

Cytotoxic and Topographical Properties of 6-Arylidene-2-dimethylaminomethylcyclohexanone Hydrochlorides and Related Compounds

Published:2004-02-01 Issue:1 Volume:19 Page:1-10
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Dimmock J.R.¹,Chamankhah M.¹,Das U.¹,Zello G.A.¹,Quail J.W.²,Yang J.²,Nienaber K.H.³,Sharma R.K.⁴,Selvakumar P.⁴,Balzarini J.⁵,De Clercq E.⁵,Stables J.P.⁶

Affiliation:

1. College of Pharmacy and Nutrition, University of Saskatchewan, Saskatoon, S7N 5C9, Saskatchewan, Canada

2. Department of Chemistry, University of Saskatchewan, Saskatoon, S7N 5C9, Saskatchewan, Canada

3. Department of Biochemistry, College of Medicine, University of Saskatchewan, Saskatoonm, S7N 5E5, Saskatchewan, Canada

4. Department of Pathology, College of Medicine and Cancer Research Unit, Saskatoon Cancer Centre, Saskatoon, S7N 4H4, Saskatchewan, Canada

5. Rega Institute for Medical Research, Katholieke Universiteit Leuven, B-3000, Leuven, Belgium

6. National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, 20892-9020, Maryland, USA

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756360310001624975

Reference51 articles.

1. 1-p-Chlorophenyl-4,4-dimethyl-5-diethylamino-1-penten-3-one hydrobromide, a sulfhydryl-specific compound which reacts irreversibly with protein thiols but reversibly with small molecular weight thiols

2. Evaluation of 2‐benzylidenecyclohexanones and 2,6‐bis(benzylidene)cyclohexanones for antitumor and cytotoxic activity and as inhibitors of mitochondrial function in yeast: Metabolism studies of (E)‐2‐benzylidenecyclohexanone

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