Targeting human DNA polymerase α for the inhibition of keratinocyte proliferation. Part 1. Homology model, active site architecture and ligand binding-Reference-Cited by-同舟云学术

Targeting human DNA polymerase α for the inhibition of keratinocyte proliferation. Part 1. Homology model, active site architecture and ligand binding

Published:2008-01-01 Issue:1 Volume:23 Page:94-100
ISSN:1475-6366
Container-title:Journal of Enzyme Inhibition and Medicinal Chemistry
language:en
Short-container-title:Journal of Enzyme Inhibition and Medicinal Chemistry

Author:

Richartz Anja¹,Höltje Monika²,Brandt Birte²,Schäfer-Korting Monika¹,Höltje Hans-Dieter²

Affiliation:

1. Institute of Pharmacy, Department of Pharmacology and Toxicology, Free University of Berlin, Berlin, Germany

2. Institute of Pharmaceutical and Medicinal Chemistry, Heinrich Heine-University of Düsseldorf, Düsseldorf, Germany

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/14756360701433414

Reference21 articles.

1. Medical therapies for non-melanoma skin cancer

2. DNA Polymerases: Structural Diversity and Common Mechanisms

3. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

4. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Molecular Mechanisms of DNA Replication and Repair Machinery: Insights from Microscopic Simulations;Advanced Theory and Simulations;2019-02-12

2. Improving Topical Non-Melanoma Skin Cancer Treatment: In vitro Efficacy of a Novel Guanosine-Analog Phosphonate;Skin Pharmacology and Physiology;2014

3. DNA Dependent DNA Polymerases as Targets for Low-Weight Molecular Inhibitors: State of Art and Prospects of Rational Design;Challenges and Advances in Computational Chemistry and Physics;2014

4. Molecular modelling studies of new potential human DNA polymerase α inhibitors;Journal of Enzyme Inhibition and Medicinal Chemistry;2010-10-20

5. Antitumor effects of guanosine-analog phosphonates identified by molecular modelling;International Journal of Pharmaceutics;2010-09