Enhanced oral bioavailability of koumine by complexation with hydroxypropyl-β-cyclodextrin: preparation, optimization, ex vivo and in vivo characterization
Author:
Affiliation:
1. School of Pharmacy, Fujian Medical University, Fuzhou, China
2. Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, School of Pharmacy, Fujian Medical University, Fuzhou, China
Funder
National Natural Science Foundation of China
Science and Technology Agency of Fujian Province
Joint Funds for the Innovation of Science and Technology, Fujian province
Publisher
Informa UK Limited
Subject
Pharmaceutical Science,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/10717544.2021.1998248
Reference42 articles.
1. Preparation and in vitro characterization of rosuvastatin calcium incorporated methyl beta cyclodextrin and Captisol® inclusion complexes
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3. Inclusion Compound of Efavirenz and γ-Cyclodextrin: Solid State Studies and Effect on Solubility
4. Development of a sensitive and rapid UPLC-MS/MS method for the determination of koumine in rat plasma: application to a pharmacokinetic study
5. Paeonol nanoemulsion for enhanced oral bioavailability: optimization and mechanism
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