Targeted delivery by pH-responsive mPEG-S-PBLG micelles significantly enhances the anti-tumor efficacy of doxorubicin with reduced cardiotoxicity-Reference-Cited by-同舟云学术

Targeted delivery by pH-responsive mPEG-S-PBLG micelles significantly enhances the anti-tumor efficacy of doxorubicin with reduced cardiotoxicity

Published:2021-01-01 Issue:1 Volume:28 Page:2495-2509
ISSN:1071-7544
Container-title:Drug Delivery
language:en
Short-container-title:Drug Delivery

Author:

Feng Qiyi¹²,Xu Junhuai³,Liu Xinyi¹²,Wang Haibo³,Xiong Junjie⁴,Xiao Kai¹²

Affiliation:

1. Precision Medicine Research Center & Sichuan Provincial Key Laboratory of Precision Medicine and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China

2. National Chengdu Center for Safety Evaluation of Drugs, West China Hospital, Sichuan University, Chengdu, China

3. College of Biomass Science and Engineering, Sichuan University, Chengdu, China

4. Department of Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu, China

Funder

National Natural Science Foundation of China

Sichuan Science and Technology Program

International Cooperation Project of Chengdu Science and Technology Bureau

Innovation Spark Project of Sichuan University

135 Project for Disciplines of Excellence, West China Hospital, Sichuan University

135 Project for Disciplines of Excellence-Clinical Research Incubation Project, West China Hospital, Sichuan University

Publisher

Informa UK Limited

Subject

Pharmaceutical Science,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/10717544.2021.2008052

Reference49 articles.

1. Remote loading of doxorubicin into liposomes by transmembrane pH gradient to reduce toxicity toward H9c2 cells

2. Stimuli-responsive polymer-doxorubicin conjugate: Antitumor mechanism and potential as nano-prodrug

3. Synthesis and characterization of a PAMAM-OH derivative containing an acid-labile β-thiopropionate bond for gene delivery

4. One-Pot Synthesis of an Acid-Labile Amphiphilic Triblock Copolymer and its pH-Responsive Vesicular Assembly

5. PEGylated Multistimuli-Responsive Dendritic Prodrug-Based Nanoscale System for Enhanced Anticancer Activity

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