ENHANZE® drug delivery technology: a novel approach to subcutaneous administration using recombinant human hyaluronidase PH20

Author:

Locke Kenneth W.1,Maneval Daniel C.1,LaBarre Michael J.1

Affiliation:

1. Halozyme Therapeutics, Inc., San Diego, CA, USA

Funder

Halozyme Therapeutics, Inc.

Publisher

Informa UK Limited

Subject

Pharmaceutical Science,General Medicine

Reference73 articles.

1. Alexion Pharmaceuticals I. (2017). Alexion and Halozyme Enter License Agreement for ENHANZE Technology. Available at: http://files.shareholder.com/downloads/ALXN/6264479688x0x966094/4E5A51B2-4A6E-4C45-83C1-1F8B8373B8C0/ALXN_News_2017_12_7_General.pdf [last accessed 7 Sep 2018].

2. Alexion Pharmaceuticals I. (2018). Alexion development programs. Available at: http://alexion.com/research-development/development-programs [last accessed 19 Nov 2018].

3. Pharmacokinetics, safety, and efficacy of subcutaneous versus intravenous rituximab plus chemotherapy as treatment for chronic lymphocytic leukaemia (SAWYER): a phase 1b, open-label, randomised controlled non-inferiority trial

4. USE OF HYALURONIDASE WITH LOCAL ANESTHESIA IN OPHTHALMOLOGY

5. The impact of extracellular matrix on the chemoresistance of solid tumors – experimental and clinical results of hyaluronidase as additive to cytostatic chemotherapy

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