1. Department of Pharmaceutical Technology, National Research Center, Cairo, Egypt;
2. Department of Pharmaceutics, Faculty of Pharmacy, October University for Modern Sciences and Arts, Cairo, Egypt;
3. Department of Oral Medicine and Periodontology, Department Faculty of Dentistry, October University for Modern Sciences and Arts, Cairo, Egypt;
4. Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University at Assiut, Assiut, Egypt