Preliminary study on fabrication, characterization and synergistic anti-lung cancer effects of self-assembled micelles of covalently conjugated celastrol–polyethylene glycol

Preliminary study on fabrication, characterization and synergistic anti-lung cancer effects of self-assembled micelles of covalently conjugated celastrol–polyethylene glycol–ginsenoside Rh2

Published:2017-01-01 Issue:1 Volume:24 Page:834-845
ISSN:1071-7544
Container-title:Drug Delivery
language:en
Short-container-title:Drug Delivery

Author:

Li Peng¹²,Zhou XiaoYue¹,Qu Ding²³,Guo Mengfei²³,Fan Chenyi²³,Zhou Tong¹,Ling Yang¹⁴

Affiliation:

1. Department of Oncology, Changzhou Cancer Hospital of Soochow University, Changzhou, P.R. China,

2. Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, P.R. China,

3. Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, P.R. China, and

4. Clinical Oncology Laboratory, Changzhou Cancer Hospital of Soochow University, Changzhou, P.R. China

Publisher

Informa UK Limited

Subject

Pharmaceutical Science,General Medicine

Link

https://tandfonline.com/doi/pdf/10.1080/10717544.2017.1326540

Reference40 articles.

1. Ginsenoside Rh2 mediates changes in the microRNA expression profile of human non-small cell lung cancer A549 cells

2. Exosomal formulation enhances therapeutic response of celastrol against lung cancer

3. Intracellular Delivery of Colloidally Stable Core-Cross-Linked Triblock Copolymer Micelles with Glutathione-Responsive Enhanced Drug Release for Cancer Therapy

4. Tumor-targeted pH/redox dual-sensitive unimolecular nanoparticles for efficient siRNA delivery

5. Phase I dose escalation and pharmacokinetic study of pluronic polymer-bound doxorubicin (SP1049C) in patients with advanced cancer

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