Hypersensitivity reactions, hepatotoxicity, and other discontinuations in persons receiving integrase strand transfer inhibitors: results from the EuroSIDA study

Author:

Pelchen-Matthews Annegret1ORCID,Larsen Jakob Friis2,Shepherd Leah1,Begovac Josip3ORCID,Pedersen Karen4,De Wit Stéphane5,Horban Andrzej6ORCID,Jablonowska Elzbieta7,Johnson Margaret8,Khromova Irina9,Losso Marcelo H.10,Nielsen Lars N.11,Ridolfo Anna Lisa12,Schmied Brigitte13,Stephan Christoph14,Yust Israel15,Curtis Lloyd16,Vannappagari Vani17,Ragone Leigh17,Roen Ashley1,Raben Dorthe2,Kirk Ole2,Peters Lars2,Mocroft Amanda12,

Affiliation:

1. Centre for Clinical Research, Epidemiology, Modelling and Evaluation (CREME), Institute for Global Health, University College London, London, UK

2. CHIP Centre of Excellence for Health, Immunity and Infections, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

3. University Hospital of Infectious Diseases, Zagreb, Croatia

4. Hvidovre Universitets Hospital, Hvidovre, Denmark

5. CHU Saint-Pierre, Brussels, Belgium

6. Wojewodzki Szpital Zakazny, Warsaw, Poland

7. Wojewodzki Szpital Specjalistyczny, Olsztyn, Poland

8. Royal Free & University College Medical School, London, UK

9. Centre for HIV/AIDS and Infectious Diseases, Kaliningrad, Russia

10. Hospital J.M. Ramos Mejia, Buenos Aires, Argentina

11. Nordsjaellands Hospital, Hillerod, Denmark

12. Ospedale L. Sacco, Milan, Italy

13. SMZ, Vienna, Austria

14. Medical Dept. 2, Infectious Diseases Unit, Goethe-University Hospital, Frankfurt, Germany

15. Ichilov Hospital, Tel Aviv, Israel

16. GlaxoSmithKline, London, UK

17. ViiV Healthcare, Research Triangle, NC, USA

Publisher

Informa UK Limited

Reference26 articles.

1. Recent Advances in the Development of Integrase Inhibitors for HIV Treatment

2. Integrase Inhibitors: After 10 Years of Experience, Is the Best Yet to Come?

3. World Health Organization Geneva Switzerland. Update of Recommendations on First- and Second-Line Antiretroviral Regimens. https://apps.who.int/iris/bitstream/handle/10665/325892/WHO-CDS-HIV-19.15-eng.pdf?ua=1. Updated July 2019. Accessed July 2020.

4. EACS (European AIDS Clinical Society). EACS Guidelines Version 10.0. https://www.eacsociety.org/guidelines/eacs-guidelines/eacs-guidelines.html. Updated November 2019. Accessed January 2021.

5. The transition to dolutegravir and other new antiretrovirals in low-income and middle-income countries

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