An integrated "4-phase" approach for setting endocrine disruption screening priorities--phase I and II predictions of estrogen receptor binding affinity

Author:

Shi‡ L.1,Tong W.1,Fang H.1,Xie Q.1,Hong H.1,Perkins R.1,Wu J.1,Tu§ M.1,Blair R.M2,Branham W.S2,Waller C.3,Walker J.4,Sheehan D.M.2

Affiliation:

1. a R.O.W. Sciences, Inc. , 3900 NCTR Road, MC910, Jefferson, AR, 72079, USA

2. b Division of Genetic and Reproductive Toxicology , National Center for Toxicological Research (NCTR) , Jefferson, AR, 72079, USA

3. c Sphinx Pharmaceuticals Division , Eli Lilly and Company , Research Triangle Park, NC, 27709, USA

4. d Interagency Testing Committee (ITC), US EPA (7401) , TSCA , Washington, DC, 20460, USA

Publisher

Informa UK Limited

Subject

Drug Discovery,Molecular Medicine,General Medicine,Bioengineering

Reference39 articles.

1. Research Needs for the Risk Assessment of Health and Environmental Effects of Endocrine Disruptors: A Report of the U.S. EPA-Sponsored Workshop

2. US-Congress. 1996. “The Food Quality Protection Act (FQPA) and the Safe Drinking Water Act (SDWA)”.

3. EDSTAC. http://www.epa.gov/opptintr/opptendo/finalrpt.htm (http://www.epa.gov/opptintr/opptendo/finalrpt.htm)

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