An integrated QSPR–PBPK modelling approach for in vitro–in vivo extrapolation of pharmacokinetics in rats
Author:
Affiliation:
1. a Groupe de recherche interdisciplinaire en santé (GRIS), Faculté de médecine , Université de Montréal , Montréal, QC, Canada
Publisher
Informa UK Limited
Subject
Drug Discovery,Molecular Medicine,General Medicine,Bioengineering
Link
https://www.tandfonline.com/doi/pdf/10.1080/10629360802547313
Reference31 articles.
1. Effets des éthers de glycol sur la reproduction
2. Worker Exposure to Volatile Organic Compounds in the Vehicle Repair Industry
3. Toxicokinetic modeling and its applications in chemical risk assessment
4. Area method for the estimation of partition coefficients for physiological pharmacokinetic models
Cited by 13 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Physiologically based pharmacokinetic models in reproductive and developmental toxicology;Reproductive and Developmental Toxicology;2022
2. Physiologically Based Pharmacokinetic Models in Reproductive and Developmental Toxicology;Reproductive and Developmental Toxicology;2017
3. The Need for Human Exposure Projection in the Interpretation of PreclinicalIn VitroandIn VivoADME Tox Data;Drug Discovery Toxicology;2016-03-24
4. Quantitative Property–Property Relationship for Screening-Level Prediction of Intrinsic Clearance: A Tool for Exposure Modeling for High-Throughput Toxicity Screening Data;Applied In Vitro Toxicology;2015-06
5. PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment;Regulatory Toxicology and Pharmacology;2014-02
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3