Prediction of acute mammalian toxicity from QSARs and interspecies correlations

Author:

Devillers J.1,Devillers H.1

Affiliation:

1. a CTIS , 3 Chemin de la Gravière, 69140 Rillieux La Pape, France

Publisher

Informa UK Limited

Subject

Drug Discovery,Molecular Medicine,General Medicine,Bioengineering

Reference76 articles.

1. COMM(2007) 675 final;Community European,2007

2. The prospects for using (Q)SARs in a changing political environment--high expectations and a key role for the european commission's joint research centre

3. QSAR models for reproductive toxicity and endocrine disruption in regulatory use – a preliminary investigation

4. Regulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC

5. Comparison of in vivo acute lethal potency and in vitro cytotoxicity of 48 chemicals

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