1. Department of Medicine, University of Cincinnati, Cincinnati, OH, USA;
2. Nuffield Department of Medicine and Oxford Respiratory NIHR BRC, University of Oxford, Oxford, UK;
3. Asthma & Airway Centre, UHN and University of Toronto, Toronto, ON, Canada;
4. Respiratory Therapeutic Area, GSK, Stockley Park, Uxbridge, UK;
5. Clinical Statistics, GSK, Stockley Park, Uxbridge, UK;
6. Clinical Pharmacology Modelling & Simulation, GSK, Stockley Park, Uxbridge, UK;
7. Respiratory Therapeutic Area, GSK, Research Triangle Park, NC, USA