A library approach for the <i>de novo</i> high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization-Reference-Cited by-同舟云学术

A library approach for the de novo high-throughput isolation of humanized VHH domains with favorable developability properties following camelid immunization

Published:2023-09-27 Issue:1 Volume:15 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Arras Paul¹²,Yoo Han Byul¹³,Pekar Lukas¹,Schröter Christian⁴,Clarke Thomas⁵,Krah Simon¹,Klewinghaus Daniel³,Siegmund Vanessa³,Evers Andreas¹,Zielonka Stefan¹²^ORCID

Affiliation:

1. Antibody Discovery & Protein Engineering, Merck Healthcare KGaA, Darmstadt, Germany

2. Institute for Organic Chemistry and Biochemistry, Technical University of Darmstadt, Darmstadt, Germany

3. Early Protein Supply & Characterization, Merck Healthcare KGaA, Darmstadt, Germany

4. ADCs & Targeted NBE Therapeutics, Merck KGaA, Darmstadt, Germany

5. Bioinformatics, EMD Serono, Billerica, MA, USA

Funder

no funding

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy