Biophysical characterization of PVR family interactions and therapeutic antibody recognition to TIGIT-Reference-Cited by-同舟云学术

Biophysical characterization of PVR family interactions and therapeutic antibody recognition to TIGIT

Published:2023-09-07 Issue:1 Volume:15 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Diong SJ J.¹^ORCID,Jashnani Aarti¹,Drake Andrew W.¹,Bee Christine²,Findeisen Felix¹,Dollinger Gavin¹,Wang Feng³,Rajpal Arvind³,Strop Pavel⁴,Lee Peter S.⁵

Affiliation:

1. Discovery Biologics, Bristol Myers Squibb, Redwood City, CA, USA

2. Biochemistry and Biophysics, Merck, South San Francisco, CA, USA

3. Large Molecule Drug Discovery, Genentech Research and Early Development, South San Francisco, CA, USA

4. Research, Tallac Therapeutics, Burlingame, CA, USA

5. Antibody Engineering, AbbVie, South San Francisco, CA, USA

Funder

no funding

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2023.2253788

Reference34 articles.

1. Checkpoint Blockade in Cancer Immunotherapy

2. TIGIT, the Next Step Towards Successful Combination Immune Checkpoint Therapy in Cancer

3. Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation

4. The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

5. A novel molecular interaction for the adhesion of follicular CD4 T cells to follicular DC

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