Functional mimetic of the G-protein coupled receptor CXCR4 on a soluble antibody scaffold
Author:
Affiliation:
1. Department of Antibody Discovery and Protein Engineering, AstraZeneca, Gaithersburg, MD, USA
2. Microbial Sciences, MedImmune, AstraZeneca, Gaithersburg, MD, USA
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2019.1596703
Reference46 articles.
1. Structural and Functional Characterization of Human CXCR4 as a Chemokine Receptor and HIV-1 Co-receptor by Mutagenesis and Molecular Modeling Studies
2. Regulation of CXCR4 signaling
3. Identification of CXCR4 Domains That Support Coreceptor and Chemokine Receptor Functions
4. Identification of the Cytoplasmic Domains of CXCR4 Involved in Jak2 and STAT3 Phosphorylation
5. HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor
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