Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment-Reference-Cited by-同舟云学术

Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment

Published:2019-11-28 Issue:1 Volume:12 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Sulea Traian¹^ORCID,Rohani Nazanin¹,Baardsnes Jason¹^ORCID,Corbeil Christopher R.¹^ORCID,Deprez Christophe¹^ORCID,Cepero-Donates Yuneivy¹^ORCID,Robert Alma¹,Schrag Joseph D.¹,Parat Marie¹^ORCID,Duchesne Mélanie¹,Jaramillo Maria L.¹^ORCID,Purisima Enrico O.¹,Zwaagstra John C.¹

Affiliation:

1. Human Health Therapeutics Research Centre, National Research Council Canada, Montreal, Quebec, Canada

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2019.1682866

Reference63 articles.

1. Influence of Affinity and Antigen Internalization on the Uptake and Penetration of Anti-HER2 Antibodies in Solid Tumors

2. Optimizing Properties of Antireceptor Antibodies Using Kinetic Computational Models and Experiments

3. Impact of Intrinsic Affinity on Functional Binding and Biological Activity of EGFR Antibodies

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