Important roles of CD32 in promoting suppression of IL-4 induced immune responses by a novel anti-IL-4Rα therapeutic antibody
Author:
Affiliation:
1. Department of Antibody and Protein Engineering, 3sBio Inc, Pudong, Shanghai, China
Funder
3sBio Inc
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://tandfonline.com/doi/pdf/10.1080/19420862.2019.1601985
Reference34 articles.
1. Investigational therapeutics targeting the IL-4/IL-13/STAT-6 pathway for the treatment of asthma
2. Dupilumab in the management of moderate-to-severe asthma: the data so far
3. THE IL-4 RECEPTOR: Signaling Mechanisms and Biologic Functions
4. Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting β2 agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial
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