An evaluation of instrument types for mass spectrometry-based multi-attribute analysis of biotherapeutics
Author:
Affiliation:
1. Process Development, Amgen, Inc., Thousand Oaks, CA, USA
Funder
supported by Amgen Inc
Publisher
Informa UK Limited
Subject
Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/19420862.2020.1783062
Reference33 articles.
1. Large-Scale Identification and Quantification of Covalent Modifications in Therapeutic Proteins
2. LC-MS/MS Peptide Mapping with Automated Data Processing for Routine Profiling of N-Glycans in Immunoglobulins
3. Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics
4. Simultaneous monitoring of oxidation, deamidation, isomerization, and glycosylation of monoclonal antibodies by liquid chromatography-mass spectrometry method with ultrafast tryptic digestion
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