Multimeric antibodies with increased valency surpassing functional affinity and potency thresholds using novel formats-Reference-Cited by-同舟云学术

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Multimeric antibodies with increased valency surpassing functional affinity and potency thresholds using novel formats

Published:2020-01-01 Issue:1 Volume:12 Page:
ISSN:1942-0862
Container-title:mAbs
language:en
Short-container-title:mAbs

Author:

Miller Ami¹,Carr Stephen²,Rabbitts Terry¹,Ali Hanif³

Affiliation:

1. Weatherall Institute of Molecular Medicine, MRC Molecular Haematology Unit, University of Oxford, John Radcliffe Hospital, Oxford, UK

2. Research Complex at Harwell, Rutherford Appleton Laboratory, Oxon, UK

3. Quadrucept Bio Limited, Cambridge, UK

Funder

Bloodwise Programme Grant

Publisher

Informa UK Limited

Subject

Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/19420862.2020.1752529

Reference31 articles.

1. Top drugs and companies by sales in 2018

2. Alternative molecular formats and therapeutic applications for bispecific antibodies

3. The making of bispecific antibodies

4. Affinity Dependence of the B Cell Response to Antigen: A Threshold, a Ceiling, and the Importance of Off-Rate

5. The coming of age of engineered multivalent antibodies

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4. In Silico–Ex Vitro Iteration Strategy for Affinity Maturation of Anti-Ricin Peptides and the SPR Biosensing Application;Toxins;2023-08-03

5. Harnessing sortase A transpeptidation for advanced targeted therapeutics and vaccine engineering;Biotechnology Advances;2023-05

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